The incident happened on Tuesday evening at 6pm aboard one of Norwegian's new Dreamliner airplanes when a mouse was spotted while the plane was preparing to take off, reported Romerikes Blad.
The flight was full with travellers eagerly wanting to make the journey from Oslo Gardermoen to JFK airport in New York.
Staff frantically began to search the cabin for the rodent, but the flight ended up being delayed by five hours until the mouse was finally captured. The flight did not leave Oslo until just after 11pm on Tuesday.
Norwegian's head of press, Charlotte Holmberg Jacobsson, confirmed to RB.no: “A mouse was discovered aboard the plane, which delayed the departure.”
Holmberg confirmed that though it was not unusual for mice to be found aboard aircraft, it did not happen often.
To explain the five hour delay, Holmberg Jacobsson explained: “In such situations, a pest control company must board the plane. The mouse needs to be found and then removed. In addition we need to check the whole plane. There are cases of mice having chewed through cables or the like."
Holmberg Jacobsson would not comment on how passengers aboard the flight reacted to the unusual delay.
Mice have disrupted flights before. In 2011 an SAS airplane from Stockholm in Sweden was delayed because of a mouse and the same airline company experienced the problem again in January 2012.
In 2009 a mouse led to two flights between New York and London being cancelled.