The flight, which was scheduled to depart Florida at 22.05 on Saturday, finally departed at 18.43pm local time on Monday, according to Norwegian's website. The 221 passengers had spent two nights holed up in airline hotels waiting for the flight.
"This is absolutely horrible for all those affected. This is an unacceptably long delay," the airline's spokesman Lasse Sandaker-Nielsen told Norway's VG newspaper.
He said that the airline had been forced to fly spare parts from London to repair the aircraft, and had been unable to lease other aircraft, partly because of the ongoing World Cup.
Norwegian was plagued by frequent delays to the Dreamliner fleet over Christmas, something it put down to teething problems in bringing in the new aircraft.
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Nonetheless, according to Sandaker-Nielsen, the longest delay experienced with the Dreamliner fleet during the first round of delays lasted about forty hours, making this week's delay a record.
Despite it's Dreamliner problems, the company revealed in its annual report in April that it had sold nine out of every ten seats on the long-haul flights.