The route will be served by a Boeing 737-700, with all of the economy class seating stripped out to make way for 44 comfortable, business-class passengers.
The flight will operate every day except for Saturdays.
“The route we have established is a tailored product for a defined market with particular travel needs,” Rickard Gustafson, the President and CEO of SAS, said in a statement.
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“The favourable timetable provides excellent connections throughout Scandinavia in both directions, while Houston is a hub for places to the south and west such as Mexico, Los Angeles, Dallas and Phoenix with the Star Alliance.”